It was shown that, even if it seems hard to think, the initial signs of lupus might seem in the blood, a blood disorder can be the initial sign that comes in patients having systemic lupus erythematosus.Systemic lupus erythematosus can show hematological symptoms like anemia, thrombocytopenia, low white blood cell counts and clotting disturbances. That is why, specialists in disorders of the blood can be of real support.

One of the most usual hematological abnormalities that can seem in persons having lupus is anemia. Anemia consists in a reduction in the number of red blood cells and it is recognized by some tests, such as, the hemoglobin concentration in blood, the hematocrit and the red blood cell count.It is recognized that anemia can have many causes, and in what concerns persons with lupus, anemia can appear simply because of a chronic inflammation, iron deficiency, prolonged uremia or hemolytic anemia. It is also recognized that fatigue, which is suffered by several patients having lupus can contribute to the apparition of anemia.

Prolonged uremia, which appears due to the fact of an impaired kidney function can lead to anemia. Anemia caused by prolonged uremia can be treated with androgens or erythropoietin, a lately developed hormone having role in the stimulation of red cell production. Often, chronic uremia can determine the apparition of far more severe forms of anemia, and that needs blood transfusions.

Prolonged inflammation, which is an important cause of anemia in patients that have lupus, hinders the production of red blood cells by the bone marrow. Simply because of this inflammation, iron, which is extremely critical in the production of hemoglobin accumulates unused in the marrow tissue. The remedy to restore regular red blood cell production is to ease the inflammatory condition.

Iron deficiency is another trigger of anemia that can seem since of the blood loss from the body. Drugs that are used in the treatment of lupus can irritate the stomach and create bleeding and from there outcomes iron-deficient anemia. Iron deficient can become also girls that have heavy or frequent menstrual periods.Anemic patients really should take some tests for blood loss from the stomach or intestines. It is crucial to do that, simply because the source of bleeding must be found and treated.Iron deficient anemia can be corrected in a brief time by taking iron tablets.

Hemolytic anemia is a condition that can appear in some men and women with lupus, typically due to antibodies directed against red blood cells. In this condition, auto-antibodies interact with the red blood cells, and the result is that the red blood cells are removed in the spleen or liver by scavenger cells.Usually, steroids like Prednisone are successful into treating this sort of anemia, but there are circumstances of patients that do not respond to the treatment, and surgical removal of the spleen could be necessary. Also in severe cases, it is necessary a blood transfusion.It is recognized that a deficiency of thrombocytes, which are tiny particles in the blood, crucial for blood clotting causes thrombocytopenia. This leads to bleeding from the gums, nose, or intestines and excessive skin bruising. As some typical signs of thrombocytopenia, we can mention petechiae and pinpoint hemorrhages in the skin.In individual with lupus, generally occurs immune thrombocytopenia. This appears simply because antibodies destroy the platelets, similarly with the destruction of the red blood cells in the autoimmune hemolytic anemia. As a treatment, we can mention steroids like Prednisone and in severe instances splenectomy might be required.

It was discovered that patients that have lupus produce an antibody known as the lupus anti-coagulant. It was seen that some patients with the lupus anti-coagulant tend to form clots abnormally condition referred to as venous thrombosis. That is a paradox that science can’t explain but.Occasionally, venous thrombosis can associate with pulmonary embolus, and especially that scenario demands treatment with anti-coagulant drugs such as heparin and Coumadin. Lupus anti-coagulant was also detected in cases of recurrent fetal loss, but it is not known if it causes the so-called habitual spontaneous abortion.

Patients with lupus can experience also some abnormalities , like granulocytopenia, which means there is a low granulocyte count, and lymphocytopenia- when there is a low number of lymphocytes. Usually, these abnormalities are harmless and without having symptoms, but there can occur severe granulocytopenia, which is usually caused by a reaction to medication. In this case, there should be stopped the intake of the causative drug, and if there is an infection, treatment with antibiotics is required.

Nowadays, there is a fantastic concern about the danger of finding AIDS by blood transfusions. It is great to know that there had been developed tests for antibodies against the virus that causes AIDS, and all the blood donors are screened for such antibodies.Of course, the safest thing that can be completed is to store your blood for later transfusion, but this is not usually practical.It is also possible in some blood banks to designate a member of the loved ones to donate blood for you, but it must be taken in consideration the possibility of blood incompatibility.

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